Explore cellular signaling mechanisms and pathway analysis tools for understanding cell communication and disease mechanisms.
Cell signaling pathways orchestrate virtually every aspect of cellular function, from growth and differentiation to apoptosis and immune responses. Understanding these pathways is fundamental to biomedical research and drug discovery.
| Pathway | Key Components | Biological Functions |
|---|---|---|
| MAPK/ERK | RAS, RAF, MEK, ERK | Cell proliferation, differentiation |
| PI3K/AKT/mTOR | PI3K, AKT, mTOR, PTEN | Cell survival, metabolism, growth |
| JAK/STAT | JAK1-3, STAT1-6 | Cytokine signaling, immune regulation |
| Wnt/β-catenin | Wnt, FZD, β-catenin, GSK3β | Development, stem cell maintenance |
| NF-κB | NF-κB, IκB, IKK | Inflammation, immune response |
| TGF-β/Smad | TGF-β, Smad2/3, Smad4 | Growth inhibition, fibrosis |
| Apoptosis | Caspases, Bcl-2, Bax, Cytochrome c | Programmed cell death |
We offer a comprehensive range of antibodies, proteins, and ELISA kits for studying these pathways, including phospho-specific antibodies for activation state detection.
The MAPK/ERK pathway is a critical signaling cascade that regulates cell proliferation, differentiation, and survival.
Learn moreThe PI3K/AKT/mTOR pathway is a central regulator of cell growth, metabolism, and survival.
Learn moreThe Wnt/β-catenin pathway regulates cell fate determination, proliferation, and stem cell maintenance.
Learn moreThe JAK/STAT pathway mediates cellular responses to cytokines and growth factors.
Learn more