.pathway-detail-page {
    padding-top: 72px;
    background: var(--off-white);
}

.pathway-header {
    background: linear-gradient(135deg, var(--dark), var(--dark-2));
    padding: 50px 5%;
    position: relative;
    overflow: hidden;
}

.pathway-header::before {
    content: '';
    position: absolute;
    inset: 0;
    background: radial-gradient(ellipse 60% 60% at 50% 50%, rgba(232, 114, 12, 0.15) 0%, transparent 60%);
}

.pathway-header h1 {
    font-family: var(--font-head);
    font-size: 2.5rem;
    color: var(--white);
    position: relative;
    margin-bottom: 15px;
}

.pathway-header .breadcrumb {
    color: var(--silver);
    font-size: 0.9rem;
    position: relative;
}

.pathway-header a {
    color: var(--orange-light);
    text-decoration: none;
}

.pathway-header a:hover {
    text-decoration: underline;
}

.pathway-content {
    max-width: 1000px;
    margin: 0 auto;
    padding: 40px 5%;
}

.pathway-section {
    background: var(--white);
    border-radius: 16px;
    padding: 40px;
    margin-bottom: 25px;
    border: 1px solid rgba(0, 0, 0, 0.06);
}

.pathway-section h2 {
    font-family: var(--font-head);
    font-size: 1.4rem;
    color: var(--dark);
    margin-bottom: 20px;
}

.pathway-section p {
    color: var(--silver);
    line-height: 1.8;
    font-size: 1rem;
    margin-bottom: 15px;
}

.pathway-section ul {
    padding-left: 20px;
    color: var(--silver);
    margin-bottom: 15px;
}

.pathway-section li {
    margin-bottom: 10px;
    line-height: 1.6;
}

.pathway-img {
    width: 100%;
    border-radius: 12px;
    margin: 25px 0;
}

.key-proteins {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 15px;
    margin-top: 20px;
}

.protein-tag {
    background: var(--off-white);
    padding: 12px 15px;
    border-radius: 8px;
    text-align: center;
    font-size: 0.85rem;
    color: var(--dark);
    font-weight: 500;
}

.biblio {
    background: var(--off-white);
    padding: 20px;
    border-radius: 10px;
    margin-top: 20px;
}

.biblio h3 {
    font-size: 1rem;
    color: var(--dark);
    margin-bottom: 12px;
}

.biblio p {
    font-size: 0.9rem;
    color: var(--silver);
    margin-bottom: 8px;
}

@media (max-width: 576px) {
    .pathway-grid {
        grid-template-columns: 1fr;
    }
}

@media (max-width: 480px) {
    .key-proteins {
        grid-template-columns: 1fr;
    }
}